One genome, two haplotypes
نویسندگان
چکیده
منابع مشابه
Human Genome Variation: Haplotypes, Linkage Disequilibrium, and Populations - Session Introduction
The working draft of a reference sequence of the human genome is nearing completion and is providing a basis for studies in a variety of domains. Computational challenges exist in all of these domains because of the massive amounts of data, the multiple often complex relationships among the types of relevant data, and the need to make the data accessible to researchers approaching the data from...
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While the bulk of the finished microbial genomes sequenced to date are derived from cultured bacterial and archaeal representatives, the vast majority of microorganisms elude current culturing attempts, severely limiting the ability to recover complete or even partial genomes from these environmental species. Single cell genomics is a novel culture-independent approach, which enables access to ...
متن کاملWhole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle Supporting Information
and Thimmapuram, Jyothi, "Whole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle Supporting Information" (2012). Cyber Center Publications. Paper 602.
متن کاملWhole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle.
Using a combination of whole-genome resequencing and high-density genotyping arrays, genome-wide haplotypes were reconstructed for two of the most important bulls in the history of the dairy cattle industry, Pawnee Farm Arlinda Chief ("Chief") and his son Walkway Chief Mark ("Mark"), each accounting for ∼7% of all current genomes. We aligned 20.5 Gbp (∼7.3× coverage) and 37.9 Gbp (∼13.5× covera...
متن کاملTwo independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels.
The recently identified apolipoprotein A5 gene (APOA5) has been shown to play an important role in determining plasma triglyceride concentrations in humans and mice. We previously identified an APOA5 haplotype (designated APOA5*2) that is present in approximately 16% of Caucasians and is associated with increased plasma triglyceride concentrations. In this report we describe another APOA5 haplo...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2011
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth0211-107